Description
Product Characteristics: SUBUNIT: Binds tightly to multiple syntaxins. Preferentially binds to syntaxin 6. SUBCELLULAR LOCATION: Cytoplasm. Membrane, Peripheral membrane protein. Cell junction, synapse, synaptosome. Note: Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic. Binds with Snap25 to form complexin. TISSUE SPECIFICITY: Widely expressed.,SNAP & SNARES,SNAP-29, Vesicle-membrane fusion protein, SNAP29, Soluble 29 kDa NSF attachment protein, Golgi SNARE of 32 kDa, Gs32
Target Information: This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]